Under vehicle perception for high level safety measures using a catadioptric camera system

In recent years, under vehicle surveillance and the classification of the vehicles become an indispensable task that must be achieved for security measures in certain areas such as shopping centers, government buildings, army camps etc. The main challenge to achieve this task is to monitor the under frames of the means of transportations. In this paper, we present a novel solution to achieve this aim. Our solution consists of three main parts: monitoring, detection and classification. In the first part we design a new catadioptric camera system in which the perspective camera points downwards to the catadioptric mirror mounted to the body of a mobile robot. Thanks to the catadioptric mirror the scenes against the camera optical axis direction can be viewed. In the second part we use speeded up robust features (SURF) in an object recognition algorithm. Fast appearance based mapping algorithm (FAB-MAP) is exploited for the classification of the means of transportations in the third part. Proposed technique is implemented in a laboratory environment

Performance improvement in VSLAM using stabilized feature points

Simultaneous localization and mapping (SLAM) is the main prerequisite for the autonomy of a mobile robot. In this paper, we present a novel method that enhances the consistency of the map using stabilized corner features. The proposed method integrates template matching based video stabilization and Harris corner detector. Extracting Harris corner features from stabilized video consistently increases the accuracy of the localization. Data coming from a video camera and odometry are fused in an Extended Kalman Filter (EKF) to determine the pose of the robot and build the map of the environment. Simulation results validate the performance improvement obtained by the proposed technique

The identification and characterization of protein tyrosine phosphatases expressed in the developing rat brain

Previous studies of the developing nervous system have shown that cell-cell and cell-matrix interactions are involved in a variety of processes such as the proliferation, migration and differentiation of neurons. While many cell surface molecules have been identified, the signal transduction mechanisms through which they alter cellular responses are poorly understood. Recent studies have described a new and large family of enzymes, protein tyrosine phosphatases (PTPases), that may play a key role in transduction of cell surface events. Opposing the actions of protein tyrosine kinases (PTKs), PTPases may determine the state of tyrosine phosphorylation of a protein and regulate its function. Within the family of PTPases, two subgroups have been characterized: low molecular weight cytoplasmic (non-receptor) PTPases and high molecular weight transmembrane (receptor) PTPases. Receptor PTPases have fibronectin type III and/or immunoglobulin-like domains in their extracellular domains, suggesting that they may have dual functions: cell adhesion and signal transduction. Such molecules may play a role in cellular recognition events that mediate the accurate assembly of the nervous system.Using PCR with degenerate primers and a neonatal rat cortex cDNA library, we have identified seven PTPases expressed in the developing rat brain. Four of these are transmembrane PTPases: LAR, LRP, RPTP gamma and CPTP1. Three are non-receptor PTPases: PTP-1, P19-PTP and SHP. Within the embryonic and early postnatal brain, the seven PTPases have overlapping, yet unique distributions. The expression of each of these genes are regulated in a temporally and spatially restricted pattern. Two PTPase genes, CPTP1 and P19-PTP, are expressed in a developmentally-regulated pattern. These two PTPases are expressed at their highest levels during neurogenesis and neuronal differentiation and are markedly down-regulated during postnatal life. Both CPTP1 and P19-PTP are widely distributed in the developing brain. In contrast, a non-receptor protein tyrosine phosphatase, PTPH1, is found in a region-specific pattern. PTPH1 is expressed in all adult thalamic nuclei generated by the dorsal thalamus and is absent in the nuclei generated from the ventral thalamus.The abundance and differential regulation of PTPase genes expressed in the developing brain suggest that they play a role in cell-cell interactions mediating neural differentiation. The comparative analysis of the expression patterns presented in this dissertation can guide further biochemical and genetic experiments that would allow a better understanding of their precise cellular function

An efficient heuristic for the multi-vehicle one-to-one pickup and delivery problem with split loads

In this study, we consider the Multi-vehicle One-to-one Pickup and Delivery Problem with Split Loads (MPDPSL). This problem is a generalization of the one-to-one Pickup and Delivery Problem (PDP) where each load can be served by multiple vehicles as well as multiple stops by the same vehicle. In practice, split deliveries is a viable option in many settings where the load can be physically split, such as courier services of third party logistics operators. We propose an efficient heuristic that combines the strengths of Tabu Search and Simulated Annealing for the solution of MPDPSL. Results from experiments on two problems sets in the literature indicate that the heuristic is capable of producing good quality solutions in reasonable time. The experiments also demonstrate that up to 33\% savings can be obtained by allowing split loads; however, the magnitude of savings is dependent largely on the spatial distribution of the pickup and delivery points

Fragile X Syndrome Therapeutics: Translation, Meet Translational Medicine

Fragile X syndrome, a common cause of intellectual disability and autism, is thought to occur due to abnormal regulation of neuronal protein synthesis. A study by Osterweil et al. (2013), in this issue, demonstrates that the HMG-CoA reductase inhibitor lovastatin can normalize protein synthesis and also reduce audiogenic seizures in Fmr1 knockout mice

A Hybrid PV-Battery/Supercapacitor System and a Basic Active Power Control Proposal in MATLAB/Simulink

Blaabjerg, Frede/0000-0001-8311-7412; sahin, mustafa ergin/0000-0002-5121-6173WOS: 000516827000129An increase in the integration of renewable energy generation worldwide brings along some challenges to energy systems. Energy systems need to be regulated following grid codes for the grid stability and efficiency of renewable energy utilization. the main problems that are on the active side can be caused by excessive power generation or unregulated energy generation, such as a partially cloudy day. the main problems on the load side can be caused by excessive or unregulated energy demand or nonlinear loads which deteriorate the power quality of the energy networks. This study focuses on the energy generation side as active power control. in this study, the benefits of supercapacitor use in a hybrid storage system are investigated and analyzed. A hybrid system in which photovoltaic powered and stored the energy in battery and supercapacitor are proposed in this study to solving the main problems in two sides. the supercapacitor model, photovoltaic model, and the proposed hybrid system are designed in MATLAB/Simulink for 6 kW rated power. Also, a new topology is proposed to increase the energy storage with supercapacitors for a passive storage system. the instantaneous peak currents energy is aimed to store in supercapacitors temporarily with this topology. the main advantages of this topology are voltage stabilization in two sides by the supercapacitors and a limitation of the battery load, which directly results in longer battery life and decreases the system cost. the simulation results are investigated for this topology.Scientific&Technological Research Council of Turkey (TUBITAK), 2219 postdoctoral research program [1059B191700997]This study was supported through the Scientific&Technological Research Council of Turkey (TUBITAK), 2219 postdoctoral research program with a 1059B191700997 application number

HPLC method development for the simultaneous analysis of amlodipine and valsartan in combined dosage forms and in vitro dissolution studies

A simple, rapid and reproducible HPLC method was developed for the simultaneous determination of amlodipine and valsartan in their combined dosage forms, and for drug dissolution studies. A C18 column (ODS 2, 10 μm, 200 x 4.6 mm) and a mobile phase of phosphate buffer (pH 3.6 , 0.01 mol L-1):acetonitrile: methanol (46:44:10 v/v/v) mixture were used for separation and quantification. Analyses were run at a flow-rate of 1 mL min-1 and at ambient temperature. The injection volume was 20 μL and the ultraviolet detector was set at 240 nm. Under these conditions, amlodipine and valsartan were eluted at 7.1 min and 3.4 min, respectively. Total run time was shorter than 9 min. The developed method was validated according to the literature and found to be linear within the range 0.1 - 50 μg mL-1 for amlodipine, and 0.05 - 50 μg mL-1 for valsartan. The developed method was applied successfully for quality control assay of amlodipine and valsartan in their combination drug product and in vitro dissolution studies.Desenvolveu-se método de HPLC rápido e reprodutível para a determinação simultânea de anlodipino e valsartana em suas formas de associação e para os estudos de dissolução dos fármacos. Utilizaram-se coluna C18 (ODS 2, 10 μm, 200 x 4,6 mm) e fase móvel tampão fosfato (pH 3,6, 0,01 mol L-1):acetonitrila: metanol para a separação e a quantificação. As análises foram efetuadas com velocidade de fluxo de 1 mL min-1 e à temparatura ambiente O volume de injeção foi de 20 μL e utilizou-se detector de ultravioleta a 240 nm. Sob essas condições, anlodipino e valsartana foram eluídas a 7,1 min e 3,4 min, respectivamente. O tempo total de corrida foi menor que 9 min. O método desenvolvido foi validado de acordo com a literatura e se mostrou linear na faixa de 0,1-50 μg mL-1 para anlodipino e de 0,05-50 μg mL-1 para valsartana. O método desenvolvido foi aplicado com sucesso para ensaios de controle de qualidade de associações de anlodipino e valsartana e nos estudos de dissolução in vitro

Some generalizations for mixed multivalued mappings

[EN] In this paper, we first introduce a new concept of KW-type m-contraction mapping. Then, we obtain some fixed point results for these mappings on M-metric spaces. Thus, we extend many well-known results for both single valued mappings and multivalued mappings such as the main results of Klim and Wardowski [13] and Altun et al. [4]. Also, we provide an interesting example to show the effectiveness of our result.Aslantaş, M.; Sahin, H.; Sadullah, U. (2022). Some generalizations for mixed multivalued mappings. Applied General Topology. 23(1):169-178. https://doi.org/10.4995/agt.2022.15214OJS16917823

A Study on Physical and Chemical Properties of Cellulose Paper Immersed in Various Solvent Mixtures

The cellulose paper treated in proportional mixture systems showed higher liquid absorption compare to only EtOH and MeOH treatments. It was approximately 40–70% and 50–91% higher for EtOH-NaOH and MeOH-NaOH treated papers, respectively. All conditions apparently bring about an effect of decreased strength for papers. The lowest tensile strength of 13.0 N/mm was found with EtOH and NaOH treated samples after 5th repeating wetting-drying stage. But, some conditions gave approximately 21–59.5% higher stretch than untreated samples. The pore size distributions of papers were evaluated with Simons stain procedure and experimental results usually consisted with sorption data. The less intense CH2–CH2- vibrations (1450–1700 cm−1) and C-C and C-O-C peak areas in FTIR spectra indicates lowering H-bonds in solvent treated and dried paper network structure